Dutch pharmacogenetics working group guideline for the gene-drug interaction of ABCG2, HLA-B and Allopurinol, and MTHFR, folic acid and methotrexate

  • Royal Dutch Pharmacists Association (KNMP): Pharmacogenetic Recommendation Text [cited 2022 2nd of January]. Available from: https://www.knmp.nl/.

  • (EACPT) EAfCPaT. [cited 2022 2nd of January]. Available from: https://www.eacpt.eu/.

  • (EAHP) EAoHP. [cited 2022 2nd of January]. Available from: https://www.eahp.eu/.

  • Amstutz U, Henricks LM, Offer SM, Barbarino J, Schellens JHM, Swen JJ, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing: 2017 Update. Clin Pharm Ther. 2018;103:210–6.

    CAS Article Google Scholar

  • Bank PCD, Caudle KE, Swen JJ, Gammal RS, Whirl-Carrillo M, Klein TE, et al. Comparison of the guidelines of the clinical pharmacogenetics implementation consortium and the Dutch pharmacogenetics working group. Clin Pharm Ther. 2018;103:599–618.

    CAS Article Google Scholar

  • Lunenburg CATC, van der Wouden CH, Nijenhuis M, Crommentuijn-van Rhenen MH, de Boer-Veger NJ, Buunk AM, et al. Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction of DPYD and fluoropyrimidines. Eur J Hum Genet. 2020;28:508–17.

    CAS Article Google Scholar

  • Swen J, Nijenhuis M, de Boer A, Grandia L, Maitland-van der Zee A, Mulder H, et al. Pharmacogenetics: From Bench to Byte— An Update of Guidelines. Clin Pharmacol Therapeutics. 2011;89:662–73.

    CAS Article Google Scholar

  • Swen J, Wilting I, de Goede A, Grandia L, Mulder H, Touw D, et al. Pharmacogenetics: From Bench to Byte. Clin Pharmacol Therapeutics. 2008;83:781–7.

    CAS Article Google Scholar

  • Matic M, Nijenhuis M, Soree B, de Boer-Veger NJ, Buunk AM, Houwink EJF, et al. Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone). Eur J Human Genet. 2021. https://doi.org/10.1038/s41431-021-00920-y. Epub ahead of print.

  • Brouwer J, Nijenhuis M, Soree B, Guchelaar HJ, Swen JJ, van Schaik RHN, et al. Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2C19 and CYP2D6 and SSRIs. Eur J Hum Genet. 2021. https://doi.org/10.1038/s41431-021-01004-7. Epub ahead of print.

  • Lin CW, Huang WI, Chao PH, Chen WW, Hsiao FY. Risk of cutaneous adverse reactions associated with allopurinol or febuxostat in real-world patients: A nationwide study. Int J Clin Pr. 2019;73:e13316.

    Article Google Scholar

  • Jung JW, Kim DK, Park HW, Oh KH, Joo KW, Kim YS, et al. An effective strategy to prevent allopurinol-induced hypersensitivity by HLA typing. Genet Med. 2015;17:807–14.

    CAS Article Google Scholar

  • Saksit N, Tassaneeyakul W, Nakkam N, Konyoung P, Khunarkornsiri U, Chumworathayi P, et al. Risk factors of allopurinol-induced severe cutaneous adverse reactions in a Thai population. Pharmacogenet Genomics. 2017;27:255–63.

    CAS Article Google Scholar

  • Keller SF, Lu N, Blumenthal KG, Rai SK, Yokose C, Choi JWJ, et al. Racial/ethnic variation and risk factors for allopurinol-associated severe cutaneous adverse reactions: a cohort study. Ann Rheum Dis. 2018;77:1187–93.

    PubMed Google Scholar

  • Inoue K, Yuasa H. Molecular basis for pharmacokinetics and pharmacodynamics of methotrexate in rheumatoid arthritis therapy. Drug Metab Pharmacokinet. 2014;29:12–9.

    CAS Article Google Scholar

  • Kloner RA, Forman MB, Gibbons RJ, Ross AM, Alexander RW, Stone GW. Impact of time to therapy and reperfusion modality on the efficacy of adenosine in acute myocardial infarction: the AMISTAD-2 trial. EurHeart J. 2006;27:2400–5.

    CAS Google Scholar

  • NCBI gene database [Internet]. NCBI: National Center for Biotechnology Information. 2021 [cited 11/08/2021]. Available from: https://www.ncbi.nlm.nih.gov/gene/.

  • Eckenstaler R, Benndorf RA. The Role of ABCG2 in the Pathogenesis of Primary Hyperuricemia and Gout-An Update. Int J Mol Sci. 2021;22:6678.

    CAS Article Google Scholar

  • Nakamura M, Fujita K, Toyoda Y, Takada T, Hasegawa H, Ichida K. Investigation of the transport of xanthine dehydrogenase inhibitors by the urate transporter ABCG2. Drug Metab Pharmacokinet. 2018;33:77–81.

    CAS Article Google Scholar

  • Chen L, Manautou JE, Rasmussen TP, Zhong XB. Development of precision medicine approaches based on inter-individual variability of BCRP/ABCG2. Acta Pharm Sin B 2019;9:659–74.

    Article Google Scholar

  • Li R, Miao L, Qin L, Xiang Y, Zhang X, Peng H, et al. A meta-analysis of the associations between the Q141K and Q126X ABCG2 gene variants and gout risk. Int J Clin Exp Pathol. 2015;8:9812–23.

    PubMed PubMed Central Google Scholar

  • Nucleotide [Internet]: Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information;[Availablefrom:https://wwwncbinlmnihgov/nuccore/EU4993501[Availablefrom:https://wwwncbinlmnihgov/nuccore/EU4993501

  • Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995;10:111–3.

    CAS Article Google Scholar

  • van der Put NM, Gabreëls F, Stevens EM, Smeitink JA, Trijbels FJ, Eskes TK, et al. A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects? Am J Hum Genet. 1998;62:1044–51.

    Article Google Scholar

  • Du B, Tian H, Tian D, Zhang C, Wang W, Wang L, et al. Genetic polymorphisms of key enzymes in folate metabolism affect the efficacy of folate therapy in patients with hyperhomocysteinaemia. Br J Nutr. 2018;119:887–95.

    CAS Article Google Scholar

  • Soukup T, Dosedel M, Pavek P, Nekvindova J, Barvik I, Bubancova I, et al. The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients. Rheumatol Int. 2015;35:1149–61.

    CAS Article Google Scholar

  • Shea B, Swinden MV, Tanjong Ghogomu E, Ortiz Z, Katchamart W, Rader T, et al. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis. Cochrane Database Syst Rev. 2013;2013:Cd000951.

    PubMed Central Google Scholar

  • Swen JJ, Nijenhuis M, van Rhenen M, de Boer-Veger NJ, Buunk AM, Houwink EJF, et al. Pharmacogenetic Information in Clinical Guidelines: The European Perspective. Clin Pharm Ther. 2018;103:795–801.

    Article Google Scholar

  • Saito Y, Stamp LK, Caudle KE, Hershfield MS, McDonagh EM, Callaghan JT, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA-B) genotype and allopurinol dosing: 2015 update. Clin Pharm Ther. 2016;99:36–7.

    CAS Article Google Scholar

  • Pharmacovigilance Working Party (PhVWP) monthly report on safety concerns, guidelines and general matters – July 2012: Allopurinol: risk of skin reactions associated with HLA-B*5801 allele: European Medicine Agency CFMPFHU, Pharmacovigilance Working Party; 2012[Availablefrom:https://wwwemaeuropaeu/en/monthly-reports-chmp-pharmacovigilance-working-party[Availablefrom:https://wwwemaeuropaeu/en/monthly-reports-chmp-pharmacovigilance-working-party

  • Khanna D, Fitzgerald JD, Khanna PP, Bae S, Singh MK, Neogi T, et al. American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia. Arthritis Care Res (Hoboken). 2012;64:1431–46.

    CAS Article Google Scholar

  • Leave a Reply

    Your email address will not be published.